Keep in mind also, here on the forums we get a topic about once every two or three months wondering WHY IS BL SO POPULAR??? And yet, on the actual Tapas site, BL is extremely popular, and the thousands of people subscribing to those comics aren't usually cringing at the typical aspects of the genre or wondering why others like it. That's just an example of how What People On These Forums Think doesn't necessarily determine What Most Readers Think.
This forum is a niche of people that doesn't always reflect the tastes of the wider internet. You could find that 70% of people on here hate a certain trope, then make a comic with that trope and still get a huge following because there are tons of people outside of this forum who don't hate it. While folks on here definitely have valuable insight as experienced creators, you also have to ask yourself, when you see an opinion or a bit of advice -- is this relevant to me and to my audience? Or is this person just not my audience?
I don't think it's a good idea to fret and change your story just because someone out there doesn't like a thing. Think about WHY they don't like it, and if you think they have a point that you agree with or not. Some people don't like stories that have a "chosen one," but that doesn't mean I need to immediately respond "oh no, maybe I shouldn't have a chosen one in my story" -- it means I should look at why they don't like it. They say it takes away the agency of the character and it's a cheap way to force the character to go on a quest without actually thinking about WHY this person might go on a quest. And if I look at that and go "oh, shoot, they're right, my character is underdeveloped because of this," then I make some changes. And if I think "oh, I see why this bothers them, but I don't think my character is cheaply forced into this quest -- I think him being a chosen one works for this story," then I wouldn't change it.
You say, "I know I can set the romance anywhere but..." and then list all the reasons why you want to set it in a school anyway. So set it in a school! You don't have to get our permission to do that. You just have to accept that the people who see "romance taking place in highschool" and tune out are not your audience.
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A lot of times when I run into this sort of advice, where the advice makes sense but I'd be nervous or unsure about implementing it in my story because I don't know if it fits, I'll sort of... think about it as a hypothetical? So okay, what if I DID follow this advice? if this story didn't take place in highschool, where else could it take place? Maybe one of these kids has a summer job and they met the others there? Maybe they all meet up for D&D on weekends? Maybe they met each other at camp? Whatever -- just think about how WOULD you make it work, and ponder what changes it would make to the story and characters -- what things wouldn't work? Is there a way you could change the characters to make it work?
And all of this is just an exercise, and it's good practice, and then you look at what you've come up with and decide if you like it or not. Either you've figured out why setting the story somewhere else wouldn't work and now you've just made a weird AU for fun, or you've figured out that actually you DO like setting the story somewhere else and you make some changes! A lot of times I think it's easy to shy away from even considering big changes like that, because we have an idea of what the story was gonna be like in our heads and immediately think "ehhhhh... but I don't know if that would work for my story....."
Actually stopping and taking a moment to explore it as a possibility can teach you a lot about how flexible this sort of stuff really is! Maybe you'll like the results, or maybe you won't, but it doesn't hurt to try it and explore the thought!