Ehhh may be leading a bit into edgy territory with the title, but I could still see the comic working completely fine if it is done tastefully (or at least as tasteful as you can get with dark humor) there's been way worse that has aired on television and has recieved praise.
I've had a complicated history with suicidal depression and I feel like for some, though there may not necessarily be any ill-intentioned content by the author, may find the title or subject too triggering? But they can simply avoid reading it, because at least with your comic's name you're blatantly stating the kind of content it will contain should they read it. I'm sorry I can't go more in depth with your work as an example, I'm sure it's wonderful, but I am one of those people who gets kinda bad when exposed to stuff like that ^w^"
I just remember being like, 7 years old when my dad gifted me a comic compilation called "The Book of Bunny Suicides" Now I can't really handle that kind of content without spiraling. So maybe with my past I'm a bit air-conditioned or bias so I may be completely wrong and be the only person who questions it.
But, ultimately at the end of the day I think you should do what you feel is in your own best interest (and what follows the upload guidelines lol) sorry I'm sure my answer wasn't very helpful ;w;