I think the structure of a person's brain and certain physical characteristics can influence their aptitude and potential in making creative stuff, but alone aren't enough; there needs to be a combination of that with careful study and practice, and an understanding that "talent" is often another thing that needs to be balanced.
Interestingly, the RAADS-R test that measures "how autistic you are" (kind of) calls what some people call "Special Interest" or "Restricted Interests", "Talent". Want to see my RAADS-R?

The red side is "autistic" and the blue side is "neurotypical". As you can see, I am an extremely talented autistic person!
...Which is...err... maybe not all it's cracked up to be. Let me explain...
At my day job, I've worked on creative stuff a lot with more neurotypical people, and the advantage of my autistic brain being more inter-connected becomes apparent. I can find a connection between two unrelated-seeming ideas way faster than they can (if they can at all), and it makes me a lot better at coming up with jokes about any given subject, even a technical one, or fixing story ideas by working out what could happen to make characters in one situation and up in another. But this skill was useless until I worked on my ability to communicate those ideas in a clear way. I had to put a lot of work into learning to draw and write so that my ideas are understandable, so honestly I think "creativity" is overrated, as a person "blessed" with an excess of it. The most popular novel genre in the world is Romance; a genre that always follows the same beats. Good execution of recognisable patterns with a little creative flair but not too much and done neatly and tastefully is what most people want, not wild creativity.
Some people have all these flashes of genius and brilliant, unique ideas; some people can follow all the agreed-on beats of "how to write a good story" like they're painting by numbers. If the person with the flashes of brilliance doesn't learn to structure and present their ideas, the painting by numbers person will tend to beat them in terms of building an audience. The very creative person needs to work hard to learn to bend their ideas into a shape where they feel like a coherent story, or a thematically coherent illustration, or work out how to get across why the disparate things they've combined can work together, and that's a hard thing to learn. The not so creative person who has learned to write just by learning all the rules, must learn to draw inspiration widely and to feel out what ideas to copy by looking at what people react to, and combine to add flavour to their stories, which is also a hard thing for them to learn.
Nobody makes great art without putting in the time and without not simply a lot of practice, but focused practice. I do firmly believe that an adult learning to draw could easily "Growth hack" and make up for not having drawn since childhood though doing more focused drawing courses. A lot of childhood drawing is spent on unfocused doodling, or drawing the same things over and over; I didn't truly start studying anatomy and stuff until well into my teens, and my progress was slow, because a person's sense of depth isn't fully developed til their mid-twenties. Learning as an adult, you could skip straight to learning to block in forms and understand perspective and the technical side of art; there are tons of books and courses on it. It's really like learning a language. Kids can learn a second language by just kind of being immersed in it for a while, but that doesn't mean an adult can't attend classes for a few years and come out fluent, and then refine their accent with training.
I don't have nearly as much natural aptitude for drawing as people think I must. I have stubby little hands with almost-clubbed thumbs and a poor sense of Proprioception (where my body is in relation to objects) that means I have to draw very small and very braced to make the pen do what I want (which art teachers hate! "Draw big! Draw from the elbow!"), I have good colour vision, but not that condition where I can see more colours than most (and I actually have an issue where I "stim" and feel a sense of bliss looking at very bright colours- hard to describe, it's like the feeling of tasting a sweet, juicy piece of fruit-, so I'm drawn to "gaudy" colour schemes and bright colour combinations a lot of people might think are tasteless or "for children", so need to carefully manage that and make my colours more appropriate for the job), and I have an okay sense for balance of light and shape, but it's mostly from study. The main thing I have is a desire to express myself through art and the ability to hyper-focus sometimes, but even that's a double-edged sword; I have to use a lot of stuff like music, videos, audio books and breaks to get through tedious tasks like inking.
My secret is: I was determined to make art that people will look at, so I found ways of doing that with the body and brain I have by seeking solutions and working really hard.