I read several of the long running webcomics everyone already knows about, like Dresden Codak, xkcd, Wondermark and Nedroid, but have started following a few newer ones recently.
The Wormworld Saga I discovered from a thread on this forum and its artwork is amazing. IT only updates a chapter at a time so I think I'll be waiting for a while for the next post though.
I also started reading Mare Internum this year, having made a mental note previously to check out The Meek, by the same artist/writer.
And I'm turning into a bit of a fan of Existential Comics too
Oh yeah, one other comic I discovered on Reddit is Cattle and the Creeping Things, whose comics aren't always brilliant but every now and then they post one that is EXACTLY tuned into my sense of humour (such as "A Day at the Rainbow Factory")