It's both man v self and man v man since the lead is struggling to learn how to control themselves while antagonists see them as a threat because of that fact.
Well, it's actually women dealing with a sexist and racist society while at war against even worse regimes - Nazis and such.
Probably Man vs Man, Man vs Self and Man vs Society all at once with Splitting Image1. There's the mysterious character using Mortimer's old plans that's a direct threat, there's the society in the kingdom that wants to get rid of problems rather than solving them at the root and accepting their targets are people, and there's all the characters confronting aspects about themselves they either had to hide or struggle with over the years.
My main character figtht against a world wide scale that wants to kill aliens and use their blood for supposedly end the energy crisis. Her half sister is also a half breed between alien and human, so she wants to protect her too...
Well thats the thing, the story is still in script but i plan on publish the comic soon.. on january
Mine would be mostly Man vs Self and Man vs Man, with a bit of Man vs Unknown/Extraterrestrial mixed in as well actually.
Obscurity? Or Worthlessness I suppose?
There is a main antagonist but that won't show up for some time.
I would have to say that for my novel the goal is to have both protagonist fight against themselves, and society. There might also be a bit of fighting against fate thrown in too.
8 days later
My main character is the Empress Dowager. 
So she's fighting against her own desires, and fighting enemies from outside and within her empire to mold society in the way she deems fit. XD
Man vs Unknow 
(Extraterrestrial didn't really match)
It's a Grim Reaper againts bad ghosts and the cause of it. so fate/gods also don't fit
Alien Fiction Man versus Fate/Gods
That is my main story, so that was my answer in the poll.
Alien Fiction: The Queen in Yellow Man vs Nature
Soulless Saint Man~ vs Man
~ footnote: "man" is very loosely defined here. The protag is a robot who is trying to kill an alien.
for now and the unknown because it depends on the circumstance because there will be different enemies
Ohhh I just finished the plot of my old series, it's MAN VS FATE/GOD. Because fate pretty much f*cked everthing up most of the time right?
oh yes, i intentionally do that 
i watch other anime then come back for one piece after two or three months 
I can select only one ;_;
But it's honestly really a combination of Man vs Self and Man vs Fate/Gods. As it's about the main character having to make changes and confront things in his own life, but in doing so causes conflicts with Fate and gods not wanting him to do that.
For my other comic it would be Man vs. Society and Man vs. Nature. As it's about 3 different social groups that mankind divided into after / as Nature is changing / destroying humanity.
Austin's main struggle in Mean Boys is definitely Man vs Self. More precisely, Man vs Anxiety. The other characters' conflicts are all Man vs Self too, now that I think about it; I guess it's a staple of coming-of-age stories.
(Also, I just really like that this type of conflict lets you have the characters screw up until they hit rock bottom and then pull themselves out of the mess they made, with or without the power of friendship or love.)
Oof, a little disappointed that there isn't any Man vs. Machine on here. I love evil technology. Course', I'm not writing that, so I guess that's my own fault, isn't it!
A reality that doesn't give this Heroine a harem to play with.
"...Show me the girls...SHOW ME THE GIIIIIIIIIIIIIIIIIIRLS!!! (TxT)"
3 months later
Currently the villain has not been introduced yet, so as for now: man vs self, somewhat literally in my case. Or you could say: friends vs self
I selected Man vs. Society.
The laws and traditions of society has caused him to have to also experience Man vs. Self, Man vs. Fate/Gods, Man vs. Tech/Machine, and Man vs. Unknown/Extraterrestrial.
Without the laws and traditions of society he wouldn't be facing anything. The laws and traditions of society are telling him that he is wrong and needs to improve. This is not the same as just wanting to improve naturally.
Man vs Self. There's technically others, but can't even begin to be accomplished before overcoming the first.
It's still too early in the comic to really read much into the themes, but I'd say that the story as I've written it swings between Man vs Man and Man vs Self. There's plenty of people that my main characters are forced to face off against; but ultimately the reason they fight at all is to escape their own shitty lives. Fanboy has spent his entire life as a dork and 'loser'; he finally sees a chance to live out his hero/power fantasy and quickly risks losing himself to his own narrative. Meanwhile McCrow has always been a man of action, but his violent and impulsive actions have left him scorned and feared by everyone he's ever cared about; with his every instinct apparently being wrong he starts viewing the accident that gave him his powers as his one chance to prove he's not the monster that his sons believe him to be.
