just do what you want i did all my main Mc's are non human charcters as is the main villian .(though he is more humanoid)
Come to think of it, there aren't many prominent webtoons with furry animal characters outside the realms of comedy. I say go for it and be an outlier! I personally love your designs and would check out your comic based on that alone.
There are lots of successful mainstream works that have animals as their main cast or as a core aspect of their setting.
So, no, this won't turn people off.
@DokiDokiTsuna says it right. Go all in & do it confidently. In fact your character design is very catering to younger readers in a good way.
I also once worried that general readers may not like my character designs and thought that at least anthro/furry lovers would look into it. What did I do differently afterwards? Nothing. I underestimate the readers' wide range of taste. 
Embrace the nakedness.
I'm pretty sure it's a turn off for some...mostly because of the degenerate side of Furry fandom.
Many reasons people avoid creations.
For example.. being monochrome. Or like anime fans who think all western animation is crap and vice versa....much like people who don't watch foriegn films with subtitles or old b&w films.
Wouldn't worry about it to be honest. Just create the world you envision. Can't please everyone!
Mind if I share one of my favorite comments placed on my anthro series (because it sums up a lot of points here):
No matter what, some people are going to have a bias toward something in your comic. And yeah, Anthro can be a definite "no" from some people and merely a hesitation with others (and a "hell yes!" from others too). It's the writing or art (or both) that are going to pull you across the finish line with readers.
Every comic has limitations on its fandom. So I wouldn't let that stop you from making the comic you want to make.
But, this isn't your first rodeo either. You have comics out there. You have readers. But if you want to branch out and see if you can pick up new readers- why not try an experiment? You can always do a poll featuring concept art in both styles (as long as you can live happily with either style) and see what more people are attracted to.
No matter what, always stay true to yourself. Your base (both future and current) loves you for you. But if you could do either style happily- why not try something new if that's where the winds are blowing you. Blind adherence to your preferences might just be navel-gazing... but it might also be exactly where you need to be.
If you're up to letting other people dictate where your style should go, I would suggest doing a poll here and getting more eyes on it in general to better inform your decision.
If you have one style you really want to do, do that (your heart will attract other hearts).
It may be a touch skeptical-sounding, but my day job is making beer packaging and I often do the same job in 3 different styles before we land on a winner. And sometimes something that didn't seem like a big deal to me in the design was so eye-catching/important to someone else. You never know. And getting out of your comfort zone will provoke growth.
As long as you're on the path you want to be on, stay on the path. Sometimes either path in the fork in the road will still get you to where you want to go. If you have a clear goal in mind, get there anyway you can.
We have beloved movies like "Toy Story" and "Cars" where the characters aren't humans or animals. I personally think you'll be just fine if that's the route you want to go down! Yes, some people may not like "furry" art but overall I don't think most would judge you. Anthro characters are pretty popular. Besides it's your series and you get the final say!
I don't like some "furry" stuff, but it doesn't mean I'm automatically put off if a series is about anthopomorphic animals. There are a bunch of things with animal characters that I like, like Mouse Guard, Duck Tales, My Little Pony, Ruby Quest etc.
I think so long as the creatures are either like... quite realistic fluffy animals like Mouse Guard, or they're cartoony looking like Duck Tales, I'm perfectly happy, so the first example in the thread I'm like "aww! That's cute! I'd read that!" So anything like Sonic the Hedgehog or Pokemon I'm happy with... and the point where it triggers my "NOPE" reaction is when the anthro characters are....drawn to be sexy.
So as soon as they like... have proportions a bit too close to a sexualised depiction of an adult human with defined muscles and prominent breasts, and it's combined with a cartoon animal face with big shiny eyes, that's the kind of stuff where a non-furry like me goes "uhhhh... okay, this is for furries, not for me, seeya!".
Like no shade intended on furries for liking that and enjoying it, but that art style, where the face is very much "cartoon animal with big cute anime eyes" but the body is "sexy human but with fur and a tail and paws" is what will immediately put a non-furry off. Like as soon as it looks a bit too much like the artist would like to have sex with the purple cartoon wolf, not accompany them on cute adventures, I'm immediately uncomfortable. About the furthest I can go is Disney's Robin Hood or Zootopia, largely because the characters are still relatively animal-like and not too muscular or with really pronounced sexual characteristics.
Of course, some non-furries will put the bar even higher and won't touch ANYTHING even a little anthro, but I think most are like me and it's all about not liking that specific furry aesthetic of very anime-animal-like face, hands and feet combined with unsettlingly human-like torso, arms and thighs. So if you don't want to get pigeonholed as a "furry artist" that's the area to avoid and either go more cartoon-like or go "they're humans but with horns and some patches of scales". Really though, there's nothing wrong with being a furry/scaly artist, furries seem like mostly decent people and they're an audience that lavishes stuff with attention and support, so it's really just whether you want to be in that niche or not.
I think some people assume animal stories are for kids. But other people also assume animal stories for older audience are just furry fandom stuff.
Personally I don't mind it but I think I am bias to the stuff with cute animals. I like Yokai Watch, Sonic, Neopets, Zootopia, that sort of stuff. I am not really a fan of the stuff that tries to be sexy. I am sort of weirded out by Goldie from Rockadoodle and Angela from Duckman. They have a sexy human body but a bird mouth. I know some people in the furry fandom can be very nice, so I am not going to shame people for liking that, it's just not for me.
You just hit me where I live, but I gotta say: throw a vest on her and you have the line. Vested Sally is the line.
Lolol
Some of the artists in the Archie Sonic comics era definitely took Sally (and others) just a smidge over the line for me
Totally. I think a bit of projection creeps in with character designs. You just know that Cleo was made hawt because the artist had a certain proclivity.
My comic could be misinterpreted as furry but when designing characters they are representations of where they grew up or their personality. Doyley is awkward so I gave him big feet for example. Midradia does have a lot of female attributes (a bit of an hour glass shape) but shes a is a dancer and in good shape.
There are bird and lizard types who are Chad's and Stacy's in design but If a design has a sexy attribute I tend to put an unattractive element into the design.
I'm evil. Haha
So like you can't make a comic that makes everyone happy: it is impossible. The fact that you've niched down into "this is for a demographic that likes anthro" is going to help you, rather than hinder you, because then you know who your audience is. A lot of people making comics for everyone have no clue who their demographic is and that hurts them in a big, big way when it comes to marketing their comic on socials.
Like I enjoy anthro stuff becuase I'm an animal person (not a furry, I surprisingly never got into that style and I just never make persona type characters because it just doesn't click for me) but I love it when someone draws me a good anthro character, and most of the cast of my own comic does not look human at all. Does it hurt my views? No, I don't think so.I can use the tag anthro on social media, I can show off these cute critters, and I know my followers love that. It's partly why they are there.
There are so many artists who draw anthro comics (like Lackadaisy, for instance) and have a pretty successful time at that. It may mean that getting discovered on Tapas/webtoon may be more difficult becuase they have a more narrow demographic here (big foot traffic, but small demographic) but you're going to be relying more on social media to get numbers anyway, since if you rely purely on the foot traffic of this site you need to do what is trending here, or wait for front page promotion. So just go with your gut on anthro, it does match the tone of the comic you were making.
Thanks. Meanwhile I'm wondering if the Dragoons are "On the line" given that even though they're not drawn to be "Hot" so to speak, they do have a more humanoid anatomy. (Though I was planning on having more diverse body styles as background characters and side characters.)
Though moreso was going for a vibe akin to Dust: An Elysian Tale, Cave Story, Undertale/Deltarune, and Solatorobo than a typical anthropomorphic thing.
Those don't cross the line for me, they're cute and fluffy and in a simple style like Undertale characters, and they're not posed or viewed in a sexy way.
Cool, thanks. Yeah, so I guess I managed to do my job in terms of trying to capture the vibe of Undertale and Cave Story then. 
I'd say just go for it and not worry about people being turned off your series because of your animal characters! I know because of that amount of hate directed towards furries online that some believe anything that could interpreted as being furry wouldn't do well and would only attract an furry audience (not saying you are a furry). But that's not the case most of the time. I myself have a series that who's main cast is mostly anthro and majority of the fans aren't actually furries. I guess it really depends on the type of series you're making and what audience you want to attract.
Personally, I'd love to see more comics with animal casts in the future, since they'll stand out more in a sea of human dominated stories. And I also wouldn't worry about having to deal with the furry hatedom. I'm not a furry myself but I have gotten my fare share of harassment all because my series could be interpreted as being "furry". It's stuff like this that has led to the conclusion that furry haters are much more toxic and cancerous than furries themselves. I could go on a whole rant about them but for the sake brevity, they're incredibly pathetic and you as an author shouldn't give those people any of you're time because they are not worth.
Hope this helps