Actually, Tapastic + Reddit hasn't really mixed well.
On most subreddits like /r/comics and /r/webcomics Tapastic links show up as spam links to the moderators of those subreddits and the posts go largely unnoticed (not even up or down voted, just ghosted). This is a problem that still exists.
More info on that here
Also a while ago someone else tried to start a Tapastic subreddit, and it still very small and pretty much dead.
So just be careful when posting links to other subreddits, always read the rules, and don't anger the mods. Links from imgur work the best on reddit even over official webcomic site links.