IT DOES MATTER!!! 

I made a mistake in the past by drawing the comic pages after scripting only two chapters (and I posted them online too ugh). After that, I had a really tough time planning the story while drawing. Hiatuses just couldn't be avoided. Mind you, I already knew the ending and the rough conflicts but I didn't know how to execute them in the way that would make sense.
Luckily I learned from my mistake and now I do these two steps before drawing comic pages:
1) Finish (and I mean finish!) the story line and scripts. Yes this could take months and years. I make sure that the conflicts in my story contribute to character development. I also need to understand my character's personality so that I can be consistent in how they behave throughout the story. Dialogues and any special gestures are detailed in my scripts, because that will help me a lot in the next step:
2) Storyboard!!!
THIS. Storyboarding is "the most important phase in a comic page", "the rest are just decorations" (quoted from a Tumblr post) and I couldn't agree more.
However, there is no need to plan out the whole series' storyboards just to start drawing. I draw my comic pages after I finish each chapter's storyboard.
Yes holy shit these are goddamn troublesome, but I am sure the creators of all those great comics/novels out there go through an even more complicated process. They really do plan every single thing, why this and that happen and most importantly, it has to make sense.
TL;DR: In creating a story, clarity is very important to you and the readers, so give a little more time to plan your entire story before drawing the comic pages