Not really, simply because unless you have a good name in the animation industry, expect to be treated like shit. Once you sell it you lose all rights. Want to draw some extra art work? you need permission, now. Want to make some extra merchandise? ask papa disney for permission. And really don't expect to make any money from said merchandise. That all goes to the company.
The person who made Making fiends, had their stuff as a web series, before being bought by nickelodeon. It was cancelled despite its good views and profits, and now the creator cant continue it online as they no longer have the rights.
Overall no it unless you get a shit ton of money upfront, and are not too attached to your work.