Let's resurface this old post!
I sketch & line my B&W comics traditionally and the rest digitally.
I use VueScan to scan, Photoshop as primary (cleaning scans, fixing linearts, color flating+shading, change flats+shades into tones, lettering) And sometimes Krita (for faster color flating+shading, also when delicate lines need to be re-drawn cos' it's better than Photoshop-- at least using from my not-so-powerful tablet pc)
For Resolutions:
I scan my custom 6.6" x 9.3" comicpages, resize and crop into 5.1" x 7.8" 600dpi, or about 3060x4700 px (that's the printing size without bleed areas)
My output dimensions for Tapas are 750x1155 + extended pixel white gaps = 765x1200 px.
I'm a bit meticulous on formating