It's interesting to see how many creators say they won't depict something they disagree with (barring obviously terrible things like glorifying rape/murder/etc).
For instance, I can't stand smoking-- I think it's unhealthy, unattractive, and I'd never do it. But I have a character who is a heavy smoker, and it's important to that character because it plays into how they handle their insecurities and stress. I'm asexual, but I write characters who are involved in sexual relationships and of varying orientations. And some characters I write are just completely unlike me and my morals/preferences in every way. Not like moustache-twirlingly evil, I just probably wouldn't be great friends with them. :u
Of course sensitive subjects should be handled with care and not just thrown in to create drama. But in my opinion, as storytellers we should be able to step outside ourselves and write characters we don't align with in terms of morals or lifestyle.