When I make a story, I try to make it for one person in mind, because I just can't satisfy everyone--that's impossible. Means my reach is small to start with, but I have noticed that with each comic and story I write, I gain a little more traction than the last. And, writing for one keeps me going. If I see that one guy liking each update (and I know who they are) then it's like "good...I don't have to drop this one."
Now if I were writing for a client, then it would matter a lot more if it was making money or followers, but since it's for me and my own learning and practice, that's not as much of an immediate problem (but, if in a few years it didn't gain traction I'd probably have to give it a soft ending and move on to something that would be more engaging and rewarding)